17α-methyltrenbolone
Methyltrienolone, also known by its chemical name 17α-methyltrenbolone, is a potent, non-aromatizable anabolic-androgenic steroid (AAS) that has never been approved for medical use or human consumption. It is structurally similar to trenbolone, a well-known steroid, but with the addition of a methyl group at the 17th carbon position, which allows it to be orally active. Despite its oral bioavailability, this alteration makes methyltrienolone one of the most hepatotoxic steroids available, posing significant risks to liver health even at very low doses.
Methyltrienolone is known for its strong binding affinity to the androgen receptor, much more so than testosterone or other steroids, making it an extremely potent anabolic agent. However, its high potency comes with a high risk of side effects, including severe liver toxicity, adverse cardiovascular effects, androgenic effects such as hair loss and acne, as well as a strong potential for negatively impacting cholesterol levels.
Due to its potency and risk profile, methyltrienolone is primarily used in scientific and medical research as a reference compound to study the androgen receptor and is not recommended for bodybuilding or performance enhancement purposes. Its use poses significant health risks, and there are safer alternatives for those looking to improve physical performance or muscle mass.
Its best avoided
Methyltrienolone (MT) is a highly potent steroid that does not convert to estrogen, known for its strong attachment to muscle and fat receptors, enhancing muscle growth and fat loss. However, its potency comes with high toxicity, making it a risky choice. Unlike its injectable cousin, Trenbolone, MT is taken orally but is not recommended for performance enhancement due to its potential for severe liver damage.
MT’s ability to bind so well to receptors theoretically makes it great for building muscle and burning fat. However, strong binding does not always mean better muscle-building, as seen with other steroids like Anadrol and Dianabol, which bind weakly but are still very effective.
The main concerns with MT are its toxicity and side effects, including its impact on sexual health and potential to increase the effects of estrogen from other steroids, even though MT itself doesn’t convert to estrogen. Its use is suggested at very low doses, if at all, and for a very short time to avoid serious liver damage.
Women should avoid MT entirely due to the risk of developing male characteristics. Anyone considering it should also think about using liver support supplements and must keep a close eye on their health through regular blood work. MT is most applicable for advanced users, such as bodybuilders close to competition, emphasizing its niche use and high risk. Despite its affordability and efficiency at low doses, the health risks make it a less desirable choice for most.
Conclusion
Conclusion: Methyltrienolone – Power with a Price Tag
Methyltrienolone stands out as one of the most potent anabolic steroids ever synthesized. For bodybuilders seeking extreme muscle hardness, strength, and definition, it promises results that few other compounds can match—even at microgram doses. Its non-aromatising structure means there’s no risk of estrogenic side effects like water retention or gynecomastia, making it especially appealing during cutting cycles.
However, that same unmatched potency comes with serious risks. Its extreme hepatotoxicity places a heavy burden on the liver, and even short-term use can be hazardous without strict precautions. Additionally, it causes strong suppression of natural testosterone, and its androgenic nature increases the likelihood of side effects like acne, aggression, and hair loss.
In conclusion, while methyltrienolone may be tempting for competitive or advanced bodybuilders chasing peak conditioning, it is not recommended for casual users or beginners. Any use should be approached with respect, medical supervision, and careful planning, ideally within the context of a well-structured cycle that includes support supplements and proper post-cycle therapy (PCT). It’s a tool best reserved for those who fully understand the trade-offs between unparalleled anabolic effects and very real health consequences.
✅ References
1. Methyltrienolone as a Specific Androgen Receptor Ligand
Bonne & Raynaud, 1975
Link:
https://pubmed.ncbi.nlm.nih.gov/171806/
2. Characterisation of Methyltrienolone Binding in Human Tissues
Menon et al., 1978
Link:
https://pubmed.ncbi.nlm.nih.gov/73547/
3. Binding of Methyltrienolone to Glucocorticoid Receptors
Mester & Mester, 1981
Link:
https://academic.oup.com/endo/article-abstract/109/5/1418/2590168
4. Methyltrienolone as a Mineralocorticoid Receptor Antagonist
Rafestin-Oblin et al., 2002
Link:
https://molpharm.aspetjournals.org/content/62/1/133
5. [3H]-Methyltrienolone Binding in Human Breast Cancer
Bojar et al., 1993
Link:
https://www.ejcancer.com/article/0277-5379(93)90018-Z/fulltext
