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Anadur (Nandrolone Hexyloxyphenylpropionate)


Anadur, closely related to Deca Durabolin, shares the base compound 19-nor-testosterone, or nandrolone. Unlike testosterone, it lacks a carbon atom in the 19th position, resulting in low estrogen conversion and stronger bonding with the anabolic receptor (AR). Anadur’s distinction from Deca Durabolin lies in its Hexyloxyphenylpropionate ester, making it among the slowest-acting nandrolone compounds due to its size. However, this also means it contains less nandrolone hormone compared to Deca Durabolin.

Nandrolone Hexyloxyphenylpropionate

Users typically favor Anadur for its gradual gains and fewer side effects, similar to Deca Durabolin. Although less common, it is still available in certain regions globally. Nandrolone boasts greater anabolic potency than testosterone, with minimal androgenic traits, presenting a ratio of 37:125.

Male users typically administer doses ranging from 200-600mg per week, with higher doses seen in advanced users. Its use is generally discouraged in females due to potential virilization effects such as increased body hair, deepened voice, acne, and clitoral hypertrophy. However, some women at Anabolic Review have reported success with ultra-low doses ranging from 25-50mg per week.

Anadur has mild side effects

Anadur’s chemical structure makes it susceptible to the 5-alpha-reductase enzyme, which converts it into dihydronandrolone (DHN). Unlike DHT, DHN is weaker and binds less strongly to the AR. The conversion rate of nandrolone to DHN is slower than that of testosterone. Thus, individuals concerned about prostate and hair loss can typically use Anadur with minimal side effects. Most users report no hair loss while using nandrolone products.

Anadur can also be converted into estrogenic compounds by the aromatase enzyme. Although some estrogen is produced, it’s significantly lower in both quantity and rate compared to testosterone, accounting for less than 20% of testosterone’s rate. Despite the low estrogen levels, it’s strongly recommended to use anti-estrogen compounds.

While estrogen and DHN production remains low, Anadur can also convert through another mechanism. Nandrolone binds strongly to the progesterone receptor, exerting agonistic effects throughout the body. Ideally, one would use an anti-progesterone compound; however, such products are not widely available at present.

Anadur is usually stacked with a testosterone

Anadur’s high affinity for the androgen receptor coupled with its lower androgenic expression means it’s usually not advised to take it without testosterone. Without sufficient androgenic effects and with its strong binding to the AR, side effects such as “Deca-Dick” (impotence), lethargy, and low sex drive may occur. Additionally, because Anadur is highly suppressive and produces three conversion products, restarting natural testosterone production during post cycle therapy can prove challenging.

Many Anabolic Review members report libido loss and retention of gains after a nandrolone-only cycle, but adding testosterone often resolves these issues by increasing androgenic expression and competing for AR binding. It’s essential to note that nandrolone binds heavily to the AR with minimal androgenic expression, requiring the addition of an androgenic compound to restore balance.

Nandrolone users frequently report joint relief, likely due to mild water retention caused by the compound. As a result, Anadur is usually favored in cycles aimed at gaining mass rather than losing fat. Additionally, due to various aromatizing products (estrogen, progesterone, and DHN), some Anabolic Review members experience fat gains when not adhering to strict diets. Nonetheless, gains from Anadur are typically steady and high quality, easily maintained with proper post cycle therapy.

Anadur uses in bodybuilding

Anadur, a slow-acting steroid closely related to Deca Durabolin, has gained some attention in bodybuilding circles due to its unique properties and potential benefits.

Anadur, akin to Deca Durabolin, is valued in bodybuilding for its gradual muscle-building effects. Its slow-release nature ensures steady progress without abrupt changes in physique.

With lower androgenic expression, Anadur tends to cause fewer side effects like acne and hair loss, making it appealing to sensitive users.

Users often find relief from joint pain due to Anadur’s mild water retention, enhancing comfort during intense workouts.

Though Anadur can convert to estrogenic compounds, its rate is typically lower than testosterone, reducing risks of water retention and gynecomastia.

Proper post-cycle therapy is essential as Anadur can suppress natural testosterone production, requiring restoration for hormonal balance.

Anadur is commonly stacked with testosterone to balance androgenic effects, ensuring libido and overall well-being are maintained during cycles.

Anadur Cycle

To optimize recovery post-cycle, many Anabolic Review members extend testosterone usage beyond the duration of nandrolone. This allows the body to clear nandrolone’s androgen receptor binding and transition to testosterone, improving recovery, as reported.

For post-cycle therapy, Clomid and/or Nolvadex are typically used. Some also include HCG before ending the cycle.

Since Anadur is a nandrolone compound, it’s important to note that some metabolites may linger in the body for up to 18 months, making it unsuitable for drug-tested athletes.

With its large fatty ester, Anadur has an active life of about four weeks. This allows for fewer injections, with some users opting for just one injection per week. However, due to lower concentrations, higher volumes or more frequent injections may be needed. While weekly injections are possible, it’s generally not recommended due to the high volume required (6-8ml), which could cause discomfort or complications.

Conclusion

Athletes using Anadur to boost performance during the off-season will appreciate its effectiveness as a mass-building agent. Despite its slow onset, the Nandrolone hormone is renowned for its ability to construct high-quality muscle tissue. This makes it a top choice for bulking phases. Anadur allows athletes to endure rigorous training sessions more effectively, which is especially beneficial during intense lifting sessions that can strain the body.

While Anadur isn’t typically favored as a cutting steroid, it still holds value. It may not produce the desired effects during cutting cycles, but its tissue preservation attributes are noteworthy. These are thanks to its protein and nitrogen-related characteristics. Additionally, Anadur boosts red blood cell count, enhancing muscular endurance, particularly helpful during stringent dieting phases. Its therapeutic benefits also alleviate discomfort associated with extreme dieting and maintaining lean conditions.

Given these benefits, the discontinuation of Anadur is puzzling. Once celebrated for its effectiveness against muscle wasting diseases, Anadur, like other Nandrolone compounds, is also effective in treating osteoporosis. Its medical advantages extend to treating anemia, intestinal disorders, and radiation-induced conditions. There’s also compelling evidence that Anadur and similar compounds speed up recovery from standard bone and muscle tissue injuries.

Hard Data

  1. Manufacturer: Various
  2. Effective Dose (Men): 200-600mgs/week (2mg/lb of Bodyweight)
  3. Effective Dose (Women): 50-100mgs/week
  4. Active life: 15 days Detection Time: Up to 18 months
  5. Anabolic/Androgenic ratio: 125:37
  6. Nandrolone base + Hexyloxyphenylpropionate ester.
  7. Molecular Weight(base): 274.4022
  8. Formula (base): C18 H26 O2 Melting Point (base): 122-124C

References

  • Comparison of the receptor binding properties of nandrolone and testosterone under in vitro and in vivo conditions.
  • Bergink EW, Janssen PS, Turpijn EW, van der Vies J.
  • Metabolism and receptor binding of nandrolone and testosterone under in vitro and in vivo conditions.
  • Bergink EW, Geelen JA, Turpijn EW.
  • New iodinated progestins as potential ligands for progesterone receptor imaging in breast cancer. Part 2: In vivo pharmacological characterization.
  • Rijks LJ, van den Bos JC, van Doremalen PA, Boer GJ, de Bruin K, Janssen AG, van Royen EA.
  • E-17 alpha-(2-[125I]iodovinyl)-19-nortestosterone: the synthesis of a gamma-emitting ligand for the progesterone receptor.
  • Hochberg RB, Hoyte RM, Rosner W
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